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Leonid
Moroz |
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| Leonid
Moroz's laboratory focuses on the mechanisms underlying the design
of nervous systems and develops innovative approaches to study the
genomic basis of neuronal identity and plasticity. We ask: (1) what
makes a neuron a neuron and why do they differ so from each other,
(2) how do they maintain such precise connections between each other,
(3) how does this fixed wiring result in such enormous neuronal plasticity
and (4) how does this contribute to learning and memory mechanisms? |
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Professor
of Neuroscience
Investigator, Neuroscience,
Chemistry & Whitney Lab for Marine Bioscience; Director
of the Center of Excellence in Genomic Sciences at the UF
Training
Postdoc - University of Leeds (UK) and University of Illinois
Ph.D. Institute of Developmental Biology, Academy of Sciences,
Moscow, Russia
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Contact
phone:
904.461.4020
office: Whitney Labs
lab: Whitney Labs
email:moroz@whitney.ufl.edu
Moroz
lab site |
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Current
projects in my lab include studies of the genomic and physiological
characterization of memory forming networks; identification
of genes controlling neuronal phenotype; development of innovative
technologies for direct single neuron molecular analysis, and
examination of the physiological mechanisms and evolution of
nitric oxide signaling in the nervous system. To address these
problems we utilize molecular and microanalytical (capillary
electrophoresis) tools for direct profiling of individual processes
and synapses, biochemical, electrophysiological and cell biology
techniques. Finally, we started characterization of the genome
in Aplysia californica (a unique model organism for
cellular and system neuroscience).
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| Research
Associates |
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| Andrea
Kohn, Ph.D. |
Research
Assistant Professor |
| Andreas
Heyland, Ph.D. |
Post-doctoral
Research Associate |
| Sami
Jezzini, Ph.D. |
Post-doctoral
Research Associate |
| Peter
Lovell, Ph.D. |
Post-doctoral
Research Associate |
| Michaela
Bodnarova, M.D. |
Visiting
Scientist |
| Yuri
Panchin, Ph.D. |
Visiting
Senior Researcher |
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Recent
Publications
On
the comparative biology of NO synthetic pathways: Parallel evolution
of NO mediated signaling. Moroz, L.L., Kohn, A.B. (2007).
In "Nitric Oxide, Advances in Experimental Biology, Volume
1. (Eds. Trimmer, B., Tota, B. & Wang, T.) Elsevier BV,
Amsterdam (In press)
Neuronal Transcriptome of Aplysia: Neuronal Compartments
and Circuitry. Moroz, L.L., Edwards, J. R., Puthanveettil,
S.V., Kohn, A.B. et al.. (2006). Cell, 127(7):1453-1467.
Deuterostome Phylogeny Reveals Monophyletic Chordates
and the New Phylum Xenoturbellida. Bourlat, S.J., Juliusdottir,
T., Lowe, C.J., Freeman, R., Aronowicz, J., Kirschner, M., Lander,
E.S., Thorndyke, M., Nakano, H., Kohn, A.B., Heyland, A., Moroz,
L.L., Copley, R.R., Telford, M.J. (2006). Nature, 444, 85-88.
The largest growth cones in the animal kingdom and dynamics
of neuronal growth in cell culture of Aplysia. Lovell,
P. and Moroz, L.L. (2006). Integrative and Comparative Biology,
46, 847-870.
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