Behavioral Neuroscience and Pharmacology TOP
| Bruijnzeel, Adrie |
Development of novel treatments for the negative affective state associated with acute and protracted drug withdrawal. In order to study drug withdrawal we use a rat intracranial self-stimulation procedure, drug self-administration procedures, and conditioned place preference and place aversion. |
| Carter, Christy |
We study translational models of declining physical and cognitive performance to investigate the role of the renin-angiotensin system, exercise, and nutrition in physical/cognitive decline and sarcopenia using genetic, pharmaceutical, nutritional and behavioral interventions. We also study pain, aging, and disability. |
| Davenport, Paul |
We study the neural and mechanical mechanisms controlling breathing and respiration, and reflex motor cough. |
| Devine, Darragh |
In one project, we use rodent models to investigate the biochemical basis of stress-induced psychopathology (e.g. major depression), with an emphasis on plasticity in limbic brain regions. In a second project, we use rodents to investigate the biochemical basis of self-injurious behavior (e.g. head banging in autism). |
| Edison, Art |
We study the chemical basis of communication and defense. Our primary laboratory model is Caenorhabditis elegans and other nematodes.
|
| Fuller, David |
Our research is aimed at understanding how neuroplasticity in the brain and spinal cord influences the control of breathing. Current projects focus on 1) mechanisms of spinal plasticity induced by cellular replacement therapy and rehabilitative training following cervical spinal cord injury; 2) mechanisms underlying spontaneous respiratory motor recovery following cervical spinal cord injury, and 3) gene delivery to respiratory motoneurons as a tool for improving breathing in certain disease states. |
| Hayward, Linda |
Our research revolves around identifying the role of neural circuits and neurotransmitters involved in integrating cardiovascular and respiratory control in both health and disease. Current interests are specifically focused on the role of orexin and monoamines in modulating cardiorespiratory function during sleep or wakefulness in adolescent and adult rodents. |
| Howland, Dena |
Molecular through behavioral approaches are used across multiple species to assess both the effects of injury and the potential for plasticity and recovery following spinal cord injury. Main emphases are on axonal growth, new circuitry, recovery of locomotor function, biomarkers, and extracellular matrix proteins. |
| Johnson, Rick |
We study the electrophysiology, neuroanatomy, and immunohistochemistry of sensory and spinal neurons which form the neural circuitry of the pelvic visceral and reproductive organs. These neural circuits are studied in animal models for spinal cord and peripheral nerve injury with an emphasis on functional recovery, neuroplasticity, and neural regeneration/repair strategies. |
| Kleim, Jeff |
The brain is a highly dynamic organ that is capable of structural and functional reorganization in response to a variety of manipulations. This neural plasticity is the mechanism by which the brain encodes experience. My laboratory examines how plasticity within rat and human motor cortex supports learning in the intact brain and “relearning” after stroke. |
| Lewis, Mark |
We study the stereotyped or inflexible repetitive behavior diagnostic of autism and commonly seen in many neurodevelopmental disorders. We are involved in both clinical and animal models studies, the latter involving examination of the genetics and neurobiology underlying the development and expression of repetitive behavior in two different mouse models. |
| Mandel, Ron |
We use rAAV vectors to model and perform translational research for neurological disorders. |
| Morgan, Drake |
We examine some of the behavioral, pharmacological, and physiological consequences of recreational (e.g. cocaine) and long-term medicinal (e.g. opioid painkiller) drug use. |
| Moroz, Leonid |
We investigate the genomic bases and principles of organization of neural circuits, learning and memory mechanisms, and the origin and evolution of nervous systems. |
| Petitto, John |
We investigate the role of immune response genes and T cells in CNS autoimmunity and neuroregeneration. |
Addiction, Autism, and other Mental Illnesses TOP
| Bruijnzeel, Adrie |
Development of novel treatments for the negative affective state associated with acute and protracted drug withdrawal. In order to study drug withdrawal we use a rat intracranial self-stimulation procedure, drug self-administration procedures, and conditioned place preference and place aversion. |
| Carney, Paul |
Students and faculty affiliated with our laboratory engage in a variety of basic scientific endeavors with a primary goal to understand the mechanisms of epilepsy and to apply this knowledge toward developing new treatments and cures. |
| Devine, Darragh |
In one project, we use rodent models to investigate the biochemical basis of stress-induced psychopathology (e.g. major depression), with an emphasis on plasticity in limbic brain regions. In a second project, we use rodents to investigate the biochemical basis of self-injurious behavior (e.g. head banging in autism). |
| Frazier, C. Jason |
We use electrophysiological and optical techniques to study neurophysiological mechanisms implicated in aging, epilepsy, and drug abuse. |
| Gold, Mark |
Our major research focus is to develop animal or laboratory models of addiction and bring them from concept to therapy. |
| Hobbs, Jacqueline |
The overall research interest of my laboratory is neurovirology. In particular, we study the basic and clinical neurobiology of the human parvoviruses and the role of viruses in major psychiatric disorders such as schizophrenia, bipolar disorder, and autism. |
| Lewis, Mark |
We study the stereotyped or inflexible repetitive behavior diagnostic of autism and commonly seen in many neurodevelopmental disorders. We are involved in both clinical and animal models studies, the latter involving examination of the genetics and neurobiology underlying the development and expression of repetitive behavior in two different mouse models. |
| Liu, Yijun |
Our research program focuses on (1) human cognition and perception involving neural timing and self processing; (2) a range of psychiatric disorders including addiction, autism, depression, eating disorders, obesity and Prader-Willi syndrome, pathological gambling and OCD, sleeping disorders and sexual dysfunction; (3) fMRI methodology: dynamic and causality analyses, connectivity analyses, and gene-brain mapping. |
| Morgan, Drake |
We examine some of the behavioral, pharmacological, and physiological consequences of recreational (e.g. cocaine) and long-term medicinal (e.g. opioid painkiller) drug use. |
| Nixon, Sara Jo |
We conduct neurocognitive studies of the brain/behavior interface in both clinical and normal populations. |
| Papke, Roger |
We study the biophysics and pharmacology of brain nicotine receptors by either expressing cloned forms of those receptors or by studying the nature receptors in fresh brain slices. Our goals are to understand the underpinnings of nicotine addiction and also to understand how to target specific nicotine receptor subtypes for the treatment of neurological diseases such as Alzheimer's or schizophrenia. |
| Petitto, John |
We investigate the role of immune response genes and T cells in CNS autoimmunity and neuroregeneration. |
Human Cognition and Perception TOP
| Liu, Yijun |
Our research program focuses on (1) human cognition and perception involving neural timing and self processing; (2) a range of psychiatric disorders including addiction, autism, depression, eating disorders, obesity and Prader-Willi syndrome, pathological gambling and OCD, sleeping disorders and sexual dysfunction; (3) fMRI methodology: dynamic and causality analyses, connectivity analyses, and gene-brain mapping. |
| Nixon, Sara Jo |
We conduct neurocognitive studies of the brain/behavior interface in both clinical and normal populations. |
Functional Neural Circuitry and Imaging TOP
| Blackband, Steve |
Our research program focuses on the development and application of magnetic resonance imaging (MRI) and microscopy (MRM) to biological systems, including single cells, isolated tissues, animal models and humans. |
| Carney, Paul |
Students and faculty affiliated with our laboratory engage in a variety of basic scientific endeavors with a primary goal to understand the mechanisms of epilepsy and to apply this knowledge toward developing new treatments and cures. |
| Davenport, Paul |
We study the neural and mechanical mechanisms controlling breathing and respiration, and reflex motor cough. |
| Frazier, C. Jason |
We use electrophysiological and optical techniques to study neurophysiological mechanisms implicated in aging, epilepsy, and drug abuse. |
| Fuller, David |
Our research is aimed at understanding how neuroplasticity in the brain and spinal cord influences the control of breathing. Current projects focus on 1) mechanisms of spinal plasticity induced by cellular replacement therapy and rehabilitative training following cervical spinal cord injury; 2) mechanisms underlying spontaneous respiratory motor recovery following cervical spinal cord injury, and 3) gene delivery to respiratory motoneurons as a tool for improving breathing in certain disease states. |
| Hayward, Linda |
Our research revolves around identifying the role of neural circuits and neurotransmitters involved in integrating cardiovascular and respiratory control in both health and disease. Current interests are specifically focused on the role of orexin and monoamines in modulating cardiorespiratory function during sleep or wakefulness in adolescent and adult rodents. |
| Howland, Dena |
Molecular through behavioral approaches are used across multiple species to assess both the effects of injury and the potential for plasticity and recovery following spinal cord injury. Main emphases are on axonal growth, new circuitry, recovery of locomotor function, biomarkers, and extracellular matrix proteins. |
| Johnson, Rick |
We study the electrophysiology, neuroanatomy, and immunohistochemistry of sensory and spinal neurons which form the neural circuitry of the pelvic visceral and reproductive organs. These neural circuits are studied in animal models for spinal cord and peripheral nerve injury with an emphasis on functional recovery, neuroplasticity, and neural regeneration/repair strategies. |
| Kleim, Jeff |
The brain is a highly dynamic organ that is capable of structural and functional reorganization in response to a variety of manipulations. This neural plasticity is the mechanism by which the brain encodes experience. My laboratory examines how plasticity within rat and human motor cortex supports learning in the intact brain and “relearning” after stroke. |
| Liu, Yijun |
Our research program focuses on (1) human cognition and perception involving neural timing and self processing; (2) a range of psychiatric disorders including addiction, autism, depression, eating disorders, obesity and Prader-Willi syndrome, pathological gambling and OCD, sleeping disorders and sexual dysfunction; (3) fMRI methodology: dynamic and causality analyses, connectivity analyses, and gene-brain mapping. |
| Liu, Zhao |
We study mechanisms underlying epileptogenesis and neuroprotection in epilepsy. |
| Moroz, Leonid |
We investigate the genomic bases and principles of organization of neural circuits, learning and memory mechanisms, and the origin and evolution of nervous systems. |
| Scheuer, Deborah |
We investigate the effects of stress and stress hormones on the central neural networks that control blood pressure and neuroendocrine function. These neural networks interconnect with, and partially overlap, those that control autonomic and neuroendocrine responses to emotionally- salient events. |
| Thompson, Floyd |
Our studies focus on understanding the neurobiological changes induced by brain injury (TBI), spinal cord injury (SCI) injury, and specific neurodegenerative diseases (Multiple Sclerosis), and the fundamental processes involved in cognitive, behavioral, and motor recovery. In addition we are committed to the development of new therapies to enhance these recovery processes. |
Epilepsy, Stroke, and Neurotoxicity TOP
| Blackband, Steve |
Our research program focuses on the development and application of magnetic resonance imaging (MRI) and microscopy (MRM) to biological systems, including single cells, isolated tissues, animal models and humans. |
| Carney, Paul |
Students and faculty affiliated with our laboratory engage in a variety of basic scientific endeavors with a primary goal to understand the mechanisms of epilepsy and to apply this knowledge toward developing new treatments and cures. |
| Hayward, Linda |
Our research revolves around identifying the role of neural circuits and neurotransmitters involved in integrating cardiovascular and respiratory control in both health and disease. Current interests are specifically focused on the role of orexin and monoamines in modulating cardiorespiratory function during sleep or wakefulness in adolescent and adult rodents. |
| Kleim, Jeff |
The brain is a highly dynamic organ that is capable of structural and functional reorganization in response to a variety of manipulations. This neural plasticity is the mechanism by which the brain encodes experience. My laboratory examines how plasticity within rat and human motor cortex supports learning in the intact brain and “relearning” after stroke. |
| Liu, Yijun |
Our research program focuses on (1) human cognition and perception involving neural timing and self processing; (2) a range of psychiatric disorders including addiction, autism, depression, eating disorders, obesity and Prader-Willi syndrome, pathological gambling and OCD, sleeping disorders and sexual dysfunction; (3) fMRI methodology: dynamic and causality analyses, connectivity analyses, and gene-brain mapping. |
| Liu, Zhao |
We study mechanisms underlying epileptogenesis and neuroprotection in epilepsy. |
| Martynyuk, Anatoly |
Our research focuses on the contribution of abnormal glutamatergic activity to the etiology of CNS disorders, such as stroke, epileptic seizures, and schizophrenia, and on drug development for their treatments. |
| Moroz, Leonid |
We investigate the genomic bases and principles of organization of neural circuits, learning and memory mechanisms, and the origin and evolution of nervous systems. |
Neurobiology of Eating and Obsesity, Sleep and Sleep Disorders, and Gender and Sex TOP
| Carter, Christy |
We study translational models of declining physical and cognitive performance to investigate the role of the renin-angiotensin system, exercise, and nutrition in physical/cognitive decline and sarcopenia using genetic, pharmaceutical, nutritional and behavioral interventions. We also study pain, aging, and disability. |
| Edison, Art |
We study the chemical basis of communication and defense. Our primary laboratory model is Caenorhabditis elegans and other nematodes.
|
| Gold, Mark |
Our major research focus is to develop animal or laboratory models of addiction and bring them from concept to therapy. |
| Hobbs, Jacqueline |
The overall research interest of my laboratory is neurovirology. In particular, we study the basic and clinical neurobiology of the human parvoviruses and the role of viruses in major psychiatric disorders such as schizophrenia, bipolar disorder, and autism. |
| Liu, Yijun |
Our research program focuses on (1) human cognition and perception involving neural timing and self processing; (2) a range of psychiatric disorders including addiction, autism, depression, eating disorders, obesity and Prader-Willi syndrome, pathological gambling and OCD, sleeping disorders and sexual dysfunction; (3) fMRI methodology: dynamic and causality analyses, connectivity analyses, and gene-brain mapping. |
| Nixon, Sara Jo |
We conduct neurocognitive studies of the brain/behavior interface in both clinical and normal populations. |
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