UF Neuroscience Department

Neuroscience News

Congratulations to Dr. Mercedes Prudencio, who successfully defended her doctoral research titled "Implication of detergent-insoluble aggregates of SOD1 in familial amyotrophic lateral sclerosis " on October 7th. Mercedes entered the Neuroscience IDP program in 2005. She is mentored by Dr. David Borchelt.

Congratulations to Dr. Shelby Suckow, who successfully defended her doctoral research titled "Identification and characterization of colospinal afferent neurons" on September 4th. Shelby entered the Neuroscience IDP program in 2005. She is mentored by Dr. Robert Caudle.

Congratulations to Dr. Kristina Aenlle who successfully defended her doctoral research titled "Estrogen treatment in the hippocampus: Analysis of gene expression and cognitive function in the aging female mouse" on August 24th. Kristina entered the Neuroscience IDP program in 2003. She is mentored by Dr. Tom Foster.

Congratulations to Dr. Arseima Del Valle-Pinero who successfully defended her doctoral research titled "N-Methyl-D-Aspartate Receptors in the Enteric Nervous System" on July 23rd. Areseima entered the Neuroscience IDP program in 2003 She is mentored by Dr. Robert Caudle.

Congratulations to Dr. Jeremy Flint, who successfully defended his doctoral research titled "Examination of Tissue Microstructure, Contrast Enhancement and Neural Activity in the Brain Slice Model Using Magnetic Resonance Microscopy" on June 26th. Jeremy entered the Neuroscience IDP program in 2004 and has one first author published paper (Neuroimage) and four additional published manuscripts. Jeremy is mentored by Dr. Stephen Blackband.

Congratulations to Dr. Kelly Miller, who successfully defended her doctoral research titled "Microglial Function in the Aged and Injured Rodent Brain" on May 19th. Kelly entered the Neuroscience IDP program in 2004 and has one first author paper in press (Neuron Glia Biology) and four additional published manuscripts. Kelly is mentored by Dr. Wolfgang Streit. We wish Kelly continued success in her postdoctoral studies. She will be moving to Charite University Berlin, Germany, to work with Dr. Frank Heppner, Director of the Institute of Neuropathology.

Congratulations to Emalick Njie who was recently awarded a research grant from the B.W. Robinson Memorial Endowment for the Neurosicences, Tallahassee Memorial Hospital Foundation, Inc. for his research titled " Neuronal stem cells as a therapeutic delivery vehicle for the Abeta degrading protease MMP9". Emalick is mentored by Dr. Wolfgang Streit.

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Recent Publications

Gene therapy for neurological disorders: challenges and future prospects for the use of growth factors for the treatment of Parkinson's disease. Manfredsson FP, Okun MS, Mandel RJ. Curr Gene Ther. 2009 Oct;9(5):375-88.
Aldehyde Dehydrogenase-Expressing Colon Stem Cells Contribute to Tumorigenesis in the Transition from Colitis to Cancer. Carpentino JE, Hynes MJ, Appelman HD, Zheng T, Steindler DA, Scott EW, Huang EH. Cancer Res. 2009 Oct 6;. [Epub ahead of print] PMID: 19808966
Immunoreactivity of the phosphorylated axonal neurofilament H subunit (pNF-H) in blood of ALS model rodents and ALS patients: Evaluation of blood pNF-H as a potential ALS biomarker. Boylan K, Yang C, Crook J, Overstreet K, Heckman M, Wang Y, Borchelt D, Shaw G. Neurochem. 2009 Sep 18;. [Epub ahead of print] PMID: 19765193
Differential Transduction Following Basal Ganglia Administration of Distinct Pseudotyped AAV Capsid Serotypes in Nonhuman Primates Dodiya HB, Bjorklund T, Stansell Iii J, Mandel RJ, Kirik D, Kordower JH. Mol Ther. 2009 Sep 22;. [Epub ahead of print] PMID: 19773746
BDNF Val66Met Polymorphism Influences Motor System Function in the Human Brain McHughen SA, Rodriguez PF, Kleim JA, Kleim ED, Crespo LM, Procaccio V, Cramer SC. Cereb Cortex. 2009 Sep 10;. [Epub ahead of print] PMID: 19745020
Brain plasticity and genetic factors. Pearson-Fuhrhop KM, Kleim JA, Cramer SC. Top Stroke Rehabil. 2009 Jul-Aug;16(4):282-99.
Spinal circuitry and respiratory recovery following spinal cord injury. Lane MA, Lee KZ, Fuller DD, Reier PJ. Respir Physiol Neurobiol. 2009 Aug 18;. [Epub ahead of print]PMID: 19698805
Tight Long-term Dynamic Doxycycline Responsive Nigrostriatal GDNF Using a Single rAAV Vector. Manfredsson FP, Burger C, Rising AC, Zuobi-Hasona K, Sullivan LF, Lewin AS, Huang J, Piercefield E, Muzyczka N, Mandel RJ. Mol Ther. 2009 Aug 25;. [Epub ahead of print] PMID: 19707186
Phrenic motoneuron discharge patterns during hypoxia-induced short term potentiation in rats. Lee KZ, Reier PJ, Fuller DD. J Neurophysiol. 2009 Aug 5;. [Epub ahead of print] PMID: 19657076
Optimization of continuous in vivo DOPA production and studies of ectopic DA synthesis using rAAV5 vectors in Parkinsonian rats. Bjorklund T, Hall H, Breysse N, Soneson C, Carlsson T, Mandel RJ, Carta M, Kirik D. J Neurochem. 2009 Aug 17;. [Epub ahead of print] PMID: 19686242
Life and Death of Microglia. Streit WJ, Xue QS. J Neuroimmune Pharmacol. 2009 Aug 14;. [Epub ahead of print] PMID: 19680817
Recovery of airway protective behaviors after spinal cord injury. Bolser DC, Jefferson SC, Rose MJ, Tester NJ, Reier PJ, Fuller DD, Davenport PW, Howland DR. Respir Physiol Neurobiol. 2009 Jul 24;. [Epub ahead of print] PMID: 19635591
Respiratory recovery following high cervical hemisection. Sandhu MS, Dougherty BJ, Lane MA, Bolser DC, Kirkwood PA, Reier PJ, Fuller DD. Respir Physiol Neurobiol. 2009 Jun 25;. [Epub ahead of print] PMID: 19560562
Comparison of single bout effects of bicycle training versus locomotor training on paired reflex depression of the soleus H-reflex after motor incomplete spinal cord injury. Phadke CP, Flynn SM, Thompson FJ, Behrman AL, Trimble MH, Kukulka CG. Arch Phys Med Rehabil. 2009 Jul;90(7):1218-28.
Expression of an Exogenous Human Oct-4 Promoter Identifies Tumor-Initiating Cells in Osteosarcoma. Levings PP, McGarry SV, Currie TP, Nickerson DM, McClellan S, Ghivizzani SC, Steindler DA, Gibbs CP. Cancer Res. 2009 Jul 7;. [Epub ahead of print] PMID: 19584295
Candidate chemoreceptor subfamilies differentially expressed in the chemosensory organs of the mollusc Aplysia. Cummins SF, Erpenbeck D, Zou Z, Claudianos C, Moroz LL, Nagle GT, Degnan BM. BMC Biol. 2009 Jun 4;7(1):28. [Epub ahead of print]PMID: 19493360
Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's disease. Streit WJ, Braak H, Xue QS, Bechmann I. Acta Neuropathol. 2009 Jun 10;. [Epub ahead of print] PMID: 19513731

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