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Molecular
Neuroscience |
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The
cells of the nervous system express a large number of distinctive
genes whose protein products define the function of these
cells. Molecular studies focus on understanding the structure
and regulation of these genes and determining the roles
that these genes play in the function of individual cells
and networks in the developing, mature and diseased nervous
system. We are engaged in studies of ion channels, neurotransmitters
and their receptors, cell-cell recognition molecules and trophic
factors, both at the genetic and protein level. Many of our investigators
utilize modern viral vector and transgenic technologies to introduce
cloned genes into the nervous system to gain insight into the role
that the encoded proteins play in the normal and diseased nervous
system.
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